11th Edition:2025
Fifty revolutionary startups converged on Singapore in 2023, each carrying transformative ideas that challenged conventional thinking across industries. The 11th Edition of the LKYGBPC celebrated ventures rewriting the rules of healthcare, sustainability, and advanced materials under the banner of RVLT50.
Grand Winners
LKY Beta Prize
MEDEA Biopharma
MEDEA Biopharma captured the LKY Beta Prize with their pioneering approach to developing novel biopharmaceutical therapies. Their platform technology addresses critical unmet medical needs, offering new hope for patients with conditions that have long resisted traditional treatment pathways. The judges recognized both the scientific rigor and commercial viability of their pipeline.
LKY Infinity Prize
PlasticFri
PlasticFri earned the LKY Infinity Prize for their mission to eliminate single-use plastics through truly biodegradable alternatives derived from natural starches. Their materials decompose completely without leaving microplastics behind, tackling one of the most visible environmental crises of our time. With scalable production already underway, PlasticFri proved that sustainability and profitability can coexist.
Other Winners
Chancellor's Cup
NEU Battery Materials
Developing next-generation battery materials that dramatically improve energy density and charging speed, NEU Battery Materials is accelerating the transition to electrified transportation and renewable energy storage at scale.
Kajima Prize
Active Surfaces
Active Surfaces transforms ordinary building facades into self-cleaning, air-purifying structures through photocatalytic coatings. Their technology turns buildings into environmental assets that actively improve urban air quality.
Best Prof-Student Venture
MirZyme Therapeutics
Born from academic research and entrepreneurial ambition, MirZyme Therapeutics develops RNA-based enzyme replacement therapies that address rare genetic diseases with unprecedented precision and patient accessibility.
Zhang Fan AI Prize
Adravision
Adravision harnesses artificial intelligence to revolutionize eye care diagnostics, enabling earlier detection of sight-threatening conditions and making specialist-level ophthalmology accessible in underserved communities worldwide.
MEET THE RVLT50 FINALISTS
Discover all 50 revolutionary startups that competed in the 11th Edition.
BETA CATEGORY
Pre-Revenue Startups
Active Surfaces
Area of Focus: Urban Solutions & Sustainability
This startup envisions a future where any surface can be solarised. It developed proprietary, Massachusetts Institute of Technology-patented flexible thin-film solar modules that are 10x lighter than comparable modules with the efficiency and stability to fight climate change.
Algrow Biosciences
Area of Focus: Urban Solutions & Sustainability
This startup creates sustainable nutrition and bio-ingredients with microalgae, using upcycled co-products in algae biorefinery. Serves as B2B ingredient supplier to 3 key markets – Alternative Protein, Alternative Pet Nutrition and High Value Compounds (Nutraceutical Cosmetics). It aims to achieve up to 85% lower cost compared with current algae incumbents.
Castomize
Area of Focus: Human Health & Potential
The startup uses proprietary 4D-printing technologies to create custom medical devices, with the aim of making healthcare more accessible, effective, and less-invasive. Their first medical device is a series of novel 4D-printed orthopaedic casts, whose shapes can custom fit to suit patients’ changing needs. The founders are featured in the Forbes 30 Under 30 List for 2023.
CBE Eco- Solutions Pte.Ltd
Area of Focus: Urban Solutions & Sustainability
CBE provides a double sustainable solution to treat industrial carbon waste (carbon soot):
CBE recycles it into high-value products instead of burning & landfill
CBE products have broad energy & environmental applications.
EmerStat
Area of Focus: Human Health & Potential
This startup developed a superhydrophobic hemostatic material that leverages nanostructural engineering to enable rapid clotting, a significant reduction in blood loss, and the risk of secondary bleeding along with the prevention of infection. With this product, the startup aims to reduce blood loss by 20x and reduce the force required to remove the patch by 420x compared to the current standard, respectively.
FLock.io
Area of Focus: Smart Nation & Digital Economy
This startup offers a financial education solution based on gamification and learn-to-earn model that helps the Gen Z to gain financial knowledge, and financial institutions to acquire financially literate customers. The startup’s goal is to establish itself as the leading financial education platform in Vietnam and reach 6 million product users by 2026.
Ingel Therapeutics
Area of Focus: Human Health & Potential
Over 250 million people worldwide are blinded by various forms of retinal degeneration. This startup wants to address this by developing an innovative cell-based therapy to bring back light to patients (Their beachhead indication is Retinitis Pigmentosa, with a future expansion including Glaucoma and dry age-related macular degeneration (AMD).
Inovative Materials
Area of Focus: Urban Solutions & Sustainability
This startup offers sustainable and environmentally responsible construction materials to address global carbon emissions and environmental problems posed by the construction industry. Hempcrete is composed of more than 90% natural ingredients (namely hemp hurds and hydrated lime), making it very convenient to recycle or to be scrapped safely, reducing the product’s waste management costs.
LiQuidium
Area of Focus: Urban Solutions & Sustainability
This startup developed a lithium-selective membrane using scalable manufacturing techniques which can be deployed in existing lithium-ion battery recycling technologies to create a circular economy. The startup helps geothermal energy producers extract 30% more lithium from their brine streams using 90% fewer chemicals, by installing ultra-durable lithium-selective membranes at a third of the production cost now.
MEDEA Biopharma
Area of Focus: Human Health & Potential
This startup is developing a new generation of sustainable and eco-friendly antibacterial solutions as alternatives to chemical and harmful antibiotics, copper and pesticides, to effectively combat harmful bacteria in humans, animals and plants. The solutions can be tailored for application in various industries including healthcare, cosmetics, food safety and agriculture.
NEU Battery Materials
Area of Focus: Urban Solutions & Sustainability
This startup achieved the world's first patented lithium battery recycling using electrochemical separation. With this technology, the process for producing battery grade lithium is up to 100x less polluting and up to 10x more profitable compared to existing recycling technologies.
NONA Technologies
Area of Focus: Urban Solutions & Sustainability
This startup is commercialising a new technology which enables a more efficient, and more durable way to remove salinity from groundwater and other brackish water sources. This helps customers save on electricity, chemical additives, and maintenance. Their product, being half the weight of the best alternative, is small can be deployed whenever water is needed, and requires 60% less power consumption to treat saline groundwater.
PEELSPHERE
Area of Focus: Urban Solutions & Sustainability
This startup has developed a material made from fruit waste and algae as an alternative to leather and synthetic leather. The material (on a per square metre basis) is made using zero chemicals, 98% less water, require up to 62% less energy, and produces 98% less CO2 emissions.
Shanghai Niantong Intelligence Co.
Area of Focus: Human Health & Potential
This startup designed a neural rehabilitation product based on a brain-computer interface to help patients relearn motor skills lost after a stroke.
Shenzhen Zhiyin accessibility technology Co, LTD
Area of Focus: Human Health & Potential
This startup developed an intelligent system developed using speech recognition, speech synthesis, gesture recognition and augmented reality to address the challenges of communication between hearing impaired and those with normal hearing.
SusMaX
Area of Focus: Urban Solutions & Sustainability
This startup uses a thermochemical process to recycle coal ash into a cost-effective better-performing lightweight aggregate (LWA) for ready-mix concrete suppliers. It is 50% lighter than normal aggregate, and can help customers achieve 50% reduction in shipping costs, increase the lifetime of concrete by 20%, and lower CO2 emissions by 50%.
Virtetic
Area of Focus: Human Health & Potential
This startup uses a thermochemical process to recycle coal ash into a cost-effective better-performing lightweight aggregate (LWA) for ready-mix concrete suppliers. It is 50% lighter than normal aggregate, and can help customers achieve 50% reduction in shipping costs, increase the lifetime of concrete by 20%, and lower CO2 emissions by 50%.
Adravision
Area of Focus: Human Health & Potential
This startup developed software that detects cavities and other dental problems on dental x-rays faster and more accurately by incorporating state-of-the-art computer vision algorithms, so dentists can focus on performing dental procedures on patients. Their pilot with 20 dentists shows a significant increase in diagnostic accuracy from 59% to 91%.
Biowerkz
Area of Focus: Urban Solutions & Sustainability
This startup developed a novel bio-based, resource-efficient, and CO2-negative material “NEWood” using only organic waste and natural binders, which can potentially save up to 30,000 trees and reduce waste disposal operational costs by 20% over 5 years.
Cauchy Analytics
Area of Focus: Human Health & Potential
This startup developed a tiny sensor that instantly generates a 3D image of the heart when placed on the patient’s chest, enabling continuous and non-invasive heart monitoring in hospital ICUs. Through the product, the startup aims to reduce global hospital costs by US$18 billion annually in North America.
Colipi
Area of Focus: Urban Solutions & Sustainability
To Feeding The World & Protecting The Climate, COLIPI is scaling a patented precision gas fermentation technology, in the realm of Carbon Capturing & Transformation (CCT), that turns carbon dioxide into edible oils (COLIPI Climate Oils), that can be used in cosmetics, foods, and petrochemical industry
Finful
Area of Focus: Smart Nation & Digital Economy
This startup offers a financial education solution based on gamification and learn-to-earn model that helps the Gen Z to gain financial knowledge, and financial institutions to acquire financially literate customers. The startup’s goal is to establish itself as the leading financial education platform in Vietnam and reach 6 million product users by 2026.
GreenCoat
Area of Focus: Smart Nation & Digital Economy Urban Solutions & Sustainability
This startup developed a next-generation plasma-coating smart window solution that dynamically changes the opacity of windows in response to real-time environmental conditions. The solution helps customers reduce their electricity costs by up to 30%, and overall, increases energy savings of up to 45% per building from reduced use of lighting and air conditioning.
IsiTwin
Area of Focus: Urban Solutions & Sustainability
This medtech startup has developed AI and engineering-based software solutions for personalised surgical planning in orthopaedics and trauma. The team aims to help surgeons define how to reduce bone fractures and optimise the quantity, characteristics and location of implantable medical devices based on the patient’s personalised characteristics through a digital twin, developed through its software.
Ki Hydrogen
Area of Focus: Urban Solutions & Sustainability
This startup developed a novel waste-to-hydrogen technology that produces green hydrogen 3x more economically than other commercially available methods. Their patented biomass electrolysis solution replaces the oxidation reaction in water electrolysis by breaking down the liquid biomass into chemical co-products. This utilises 75% less energy and is safer as no oxygen is produced during the process.
MassPrint Technology Group
Area of Focus: Manufacturing, Trade & Connectivity: Industry 4.0
This startup offers a financial education solution based on gamification and learn-to-earn model that helps the Gen Z to gain financial knowledge, and financial institutions to acquire financially literate customers. The startup’s goal is to establish itself as the leading financial education platform in Vietnam and reach 6 million product users by 2026.
MirZyme Therapeutics
Area of Focus: Human Health & Potential
This startup is using its proprietary predictive tools and creating targeted therapeutics with companion diagnostics for the management of preeclampsia for which there is no cure. They have 5 assets, 10 global patents and an Innovation Passport from the Medicines and Healthcare products Regulatory Agency of the United Kingdom for the prevention of preeclampsia.
Node Bio
Area of Focus: Urban Solutions & Sustainability
This startup uses cutting edge plant science to develop crop treatments that make agriculture more climate-resilient, productive, and sustainable. Their first product helps plants thrive despite climate shocks like drought and heat waves.
Ozonebio
Area of Focus: Urban Solutions & Sustainability
This clean-tech startup has formulated emission-free adipic acid (a first in the world), which can be used in the manufacture of food and apparel.
Plastalyst
Area of Focus: Urban Solutions & Sustainability
This startup developed a green, safe and efficient chemical catalyst that decomposes plastic waste at a lower temperature than conventional alternatives.
SHENZHEN VIBROSURGERY INSTRUMENT CO. LTD
Area of Focus: Human Health & Potential
This startup developed an ultrasonic orthopedic scalpel that combines cavitation and impact effects to remove bone tissue with minimal damage. It improves the operability and safety of surgery, and is widely used in multiple operations.
Super Nova
Area of Focus: Urban Solutions & Sustainability
This startup is involved in the industrialisation of novel aqueous ion batteries with a long lifespan and a wide temperature range.
Sylvarum
Area of Focus: Urban Solutions & Sustainability
This startup is developing electrostimulation technology with artificial intelligence to control the metabolism of plants to improve crop yields for Controlled Environment Agriculture producers. The technology can help plants grow 23% more biomass.
YaBEZ
Area of Focus: Human Health & Potential
This startup has developed a natural, topical steroid-free treatment option for Psoriasis and skin inflammatory diseases. The product can potentially help 125 million Psoriasis patients.
INFINITY CATEGORY
Post Revenue Startups
Adaptop
Area of Focus: Media & Entertainment
This startup developed a unique docking station that packs tremendous performance, extensive connectivity, and blazing fast storage, putting everything users need within easy reach in one solution. Certified by Apple and Intel, the Adaptop AIO is the first and only Thunderbolt product which combines the performance of a graphic card and the versatility of a docking station.
BloomAlert
Area of Focus: Urban Solution & Sustainability
This startup helps strengthen the role of desalination industry with a safe solution to face the world’s water crisis. As the first in the world to promote desalination sustainability through satellite intelligence, it offers an early warning system that reduces water production loss of up to 30%.
Fishyu
Area of Focus: Manufacturing, Trade & Connectivity
This startup built a seafood trading platform which aims to solve two problems: unfair prices for fishermen and excessive markups for processed factories, by connecting local fishermen directly to processing factories via a web application. Through the platform, fishermen will receive 20% of their catch’s margin price, hence selling their catch at a better price compared to selling through local distributors.
Karla Bionics
Area of Focus: Human Health & Potential
This is a startup with a vision to empower the disabled through accessible assistive devices. Their current product is the Raga Arm, a functional, intuitive prosthetic arm with a lightweight bionic-like design. Raga Arm’s versatile gripping technology helps users activate the gripping function intuitively and allows them to access 6 main grip types without the need to change or reset the device.
Magorium Pte Ltd
Area of Focus: Urban Solution & Sustainability
This startup converts contaminated plastic waste into a new material, NEWBitumen, to build green roads. By end 2022, the startup has paved 4 green roads in Singapore, and has diverted more than 8,000 kg of plastic waste from incineration.
MitoWorld
Area of Focus: Media & Entertainment
This startup developed a no-code browser based Integrated Virtual World Platform that simplifies the creation and connection of purpose driven metaverses. Its features allow users to select a blueprint design for their metaverse, upload content such as images, videos, 3D models, and launch their metaverse on a browser. The platform’s versality enables businesses to apply the metaverse for brand & product engagements, events, exhibitions, marketing campaigns, and digital twin adoption.
Pangaea Data
Area of Focus: Human Health & Potential
This startup has a novel AI-driven product which characterises patients by automatically discovering clinical signatures (which clinicians currently ascertain manually) across 4,000 hard-to-diagnose conditions in an evolving, privacy-preserving and scalable manner. By utilising the product, clinicians around the world are able to discover more patients for screening while saving time and enterprise costs by 90%.
PlasticFri
Area of Focus: Urban Solution & Sustainability
This startup is a greentech company with a breakthrough technology that turns agricultural waste into eco-friendly products, such as cups, straws, packaging to replace plastics. To date, the company has sold more than 10 million products, saved more than 52,000 litres of water and eliminated 5,000 kg of plastic waste.
Releaf Paper
Area of Focus: Urban Solution & Sustainability
This startup developed a patented technology to turn leafy biomass into fibre for paper production without cutting trees. Products can be recycled up to 5x and decomposed within 60 days. This technology uses 15x less water and 3x less energy. Reduces CO2 emissions by 78% compared to traditional paper manufacturing.
Tianjin Hermos Technology Co.
Area of Focus: Urban Solution & Sustainability
This startup offers carbon dioxide emission reduction technology solutions for carbon emitting enterprises in the industrial and energy fields. To date, the startup’s product has helped more than 10 enterprises reduce 1.3 million tonnes of CO2 emissions.
Voyawave Optics
Area of Focus: Manufacturing, Trade & Connectivity: Industry 4.0
This startup is a supplier of multi-dimensional beam editing technology and instrument application solutions, committed to developing high-efficiency, high-precision intelligent laser sources and helping the optical intelligent fabrication chain.
Aliene Pte Ltd
Area of Focus: Manufacturing, Trade & Connectivity: Industry 4.0
This spacetech startup is offering access to affordable and reliable high-quality satellite data for sustainable development through power-and fuel-efficient plasma propulsion that allows small satellites to fly closer to earth.
ElectricFish
Area of Focus: Urban Solution & Sustainability
This startup developed an easily-installed ultra-fast EV charger that is battery-storage integrated. It completed a pilot programme with the Los Angeles Department of Water & Power, helping to convert a 5 kilowatt (kW) outlet to a 350 kW charging port in 2 days instead of 2 years.
Huaxia Semiconductors
Area of Focus: Urban Solution & Sustainability
This startup is a high-tech enterprise specialising in the R&D and production of high-purity gallium (Ga) and gallium nitride (GaN) substrate materials for semiconductor integrated circuits. The company aspires to disrupt the global GaN market that underpins the 3rd generation of semiconductor materials.
LEAFYPOLYMER
Area of Focus: Urban Solution & Sustainability
This startup is a high-tech enterprise specialising in the R&D and production of high-purity gallium (Ga) and gallium nitride (GaN) substrate materials for semiconductor integrated circuits. The company aspires to disrupt the global GaN market that underpins the 3rd generation of semiconductor materials.
Messenger Bio
Area of Focus: Human Health & Potential
This startup is industrialising the discovery of mRNA-based programmable medicines. The goal is to unlock cures for thousands of genetically defined diseases that currently lack treatments. The startup has 30 institutional customers in 9 countries.
NeuroWeave
Area of Focus: Human Health & Potential
This startup is committed to researching and developing cutting-edge artificial intelligence and neuroscience technologies for the diagnosis and intervention of neurodegenerative diseases. It aims to benefit 250 million senior citizens across China through the detection of neurodegenerative diseases from the general screening population.
Pic-A-Talk
Area of Focus: Human Health & Potential
This startup has developed an educational mobile application assisting children in speech and language development. Fully digital, customisable, user-friendly and available in multiple languages, the app can also be used by teenagers and adults diagnosed with speech and language disorders, autism spectrum disorder (ASD), and learning disabilities. The startup is hopes to help children with ASD, both in the Philippines and the rest of Southeast Asia.
PLEXUS
Area of Focus: Smart Nation & Digital Economy
PLEXUS is a cross-chain aggregator and middleware infra that combines DEXs and Bridges in all chains. It enables users and companies to transfer all tokens at the fastest and most affordable price in just one click or API between any chain.
Savyn
Area of Focus: Human Health & Potential
This startup uses neuroscience-based digital therapies to reduce Post Traumatic Stress Disorder symptoms. Early trial data has shown patient outcomes on Savyn’s platform are equal to in-person therapy. The startup launched its beta product in April this year which has recorded more than 40,000 visits.
VOMMA
Area of Focus: Manufacturing, Trade & Connectivity
The core product of this startup is a light-field camera that uses computational imaging technology to achieve the instantaneous recording of multi-dimensional light information. It is capable of single shooting and instantaneous three-dimensional modelling, and features micro-nano precision, millisecond calculation and passive measurement.
Highlights: 11th Edition
IDEAS THAT MATTER | IMPACT THAT LASTS | INNOVATION WITH PURPOSE
